Publications

ReformAb

• A method for rapid, ligation-independent reformatting of recombinant monoclonal antibodies - Download here

Epi-CHO

• Epi-CHO, an episomal expression system for recombinant protein production in CHO cells - Download here
• Enhanced CHO cell-based transient gene expression with the Epi-CHO expression system - Download here
• Efficient mAb production in CHO cells incorporating PEI-mediated transfection, mild hypothermia and the co-expression of XBP-1 - Download here

FACS Capabilities/Rapid Clonal Isolation

• High-throughput clonal selection of recombinant CHO cells using a dominant selectable and amplifiable metallothionein-GFP fusion protein - Download here
• Accelerated cell line development using two-color Fluorescence Activated Cell Sorting to select highly expressing antibody-producing clones - Download here
• Intraclonal protein expression heterogeneity in recombinant CHO cells - Download here